News — Lawrenceville, NJ, USA—April 8, 2025—, the official journal of , announced today the publication of a special themed section of research papers that provide crucial insights into the complex health economics of Alzheimer's disease and related dementias (ADRD), offering a roadmap for future research and policy as the aging population grows and novel treatments emerge. Guest editors for the themed section are Thomas Rapp, PhD, Université Paris Cité, Chaire AgingUP!, and LIRAES, Paris, France, and Pei-Jung Lin, PhD, Center for the Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, USA. The series was published in the April 2025 issue of .

"As the aging population grows and novel diagnostic and treatment options emerge, understanding the complex economic implications of ADRD becomes increasingly critical," noted Rapp and Lin in their . “Conventional methods are often limited in capturing the full spectrum of costs and health impacts of ADRD, necessitating the adoption of new frameworks, broader considerations of economic outcomes, and an unwavering focus on health equity. The collection of articles in this themed section provides insights into these critical areas, providing a roadmap for future research and policy.”  

The themed section presents 8 research papers in 3 groupings:

Group 1: Refining frameworks for evaluating ADRD interventions

  1. “,” by R Handels, WL Herring, F Kamgar, and colleagues
  2. ",” by R Handels, WL Herring, S Grimm, and colleagues

 Group 2: Broadening the lens: measuring the broader economic impact of ADRD

  1. “,” by J Fox, ES Mearns, J Li, and colleagues
  2. "," by M Pfaff, W Hoffmann, M Boekholt, and colleagues
  3. "," by L Zumeta-Olaskoaga, O Ibarrondo, R del Pozo, A Zapiain, I Larrañaga, and J Mar
  4. “,” by A Cheneau and T Rapp

Group 3: Addressing health equity in ADRD care innovations

  1. “,” by Y Zhu, N Olchanski, KM Freund, JT Cohen, PJ Neumann, and P-J Lin
  2. “,” by R Haque, K Alam, J Gow, C Neville, and SA Keramat

 The collection of articles in this themed section illuminates challenges and opportunities in ADRD health economics. Moving forward, several priorities emerge: standardizing economic evaluation methodologies, developing more comprehensive approaches to measuring economic impact, and ensuring equitable access to care innovations.

"With the population aging, these priorities are becoming essential to ensure the sustainability of future healthcare spending for older people impacted by ADRD,” note the editors. “Indeed, as several innovations (pharmaceutical treatments for early stages of Alzheimer's disease, diagnosis tools using artificial intelligence algorithms, etc) are arriving on the healthcare markets, the need for a more accurate estimation of the potential economic benefits associated is becoming critical. We hope this themed section catalyzes further research, dialogue, and policy development to improve the lives of individuals affected by ADRD and their families."

Further Reading

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ABOUT VALUE IN HEALTH
(ISSN 1098-3015) is an international, indexed journal that publishes original research and health policy articles that advance the field of health economics and outcomes research to help healthcare leaders make evidence-based decisions. The journal’s current impact factor score is 4.9 and its 5-year impact factor score is 5.6. Value in Health is ranked 5th of 118 journals in Health Policy and Services, 15th of 174 journals in Health Care Sciences and Services, and 56th of 597 journals in Economics. Value in Health is a monthly publication that circulates to more than 55,000 readers around the world.
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