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IAFNS supports collaboration with academia, industry, government agencies and other labs to advance gut microbiome discoveries with an eye to new medical treatments.

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Liver transplants are becoming a new treatment option for certain colorectal cancer patients whose cancer has spread to their liver and are ineligible for other surgical options. This innovative approach is providing hope to colorectal cancer patients who otherwise are often faced with a grim prognosis.

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Regular physical activity after treatment for stage 3 colon cancer reduces and may even eliminate disparities in survival between those with cancer and those in a general population of similar age and sex, according to new Dana-Farber Cancer Institute research.

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Research in mice identifies protein responsible for regulating gut movement in response to pressure, exercise, and inflammation. The findings can inform precision-targeted treatments for intestinal inflammation and disorders of gut motility. The results add to a growing body of research showing the nervous and immune systems interact in various organs, including the brain, lungs, and skin.

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Yale Department of Surgery oncologists and trainees at Yale Cancer Center will present new findings at the Society of Surgical Oncology (SSO) Annual Meeting in Tampa, Fla., from March 27鈥�29. The conference focuses on improving surgical cancer care for patients through educational sessions as well as oral and poster presentations for surgical oncologists, researchers, and patient advocates.

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A recent study has revealed how Epstein-Barr virus (EBV) intensifies ulcerative colitis (UC), a debilitating inflammatory bowel disease. Researchers discovered that EBV infection triggers macrophage pyroptosis鈥攁 form of inflammatory cell death鈥攂y accelerating glycolysis, a key metabolic pathway.

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A team of researchers from Cleveland Clinic Genomic Medicine share insights from an early set of 19,000 patients to receive immune checkpoint inhibitor treatments for colorectal cancer in the U.S. The report comes from the laboratory of Stephanie Schmit, PhD, MPH, and was published in JAMA Network Open. It serves as an opportunity to better understand how immune checkpoint inhibitor treatments, including PD-1 and PD-L1 inhibitors, work in a larger population that reflects real-world settings. Dr. Schmit collaborated with a team of researchers that included Moffitt Cancer Center.

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Un descubrimiento realizado por investigadores de Mayo Clinic puede ayudar a explicar por qu茅 la inmunoterapia no ha sido 煤til para muchos pacientes con c谩ncer colorrectal metast谩sico. En los descubrimientos publicados en Clinical Cancer Research, el equipo identific贸 prote铆nas espec铆ficas 鈥� fibronectina y actina del m煤sculo liso 鈥� dentro de los tejidos del c谩ncer colorrectal que est谩n asociadas con la resistencia al tratamiento de inmunoterapia.

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La enfermedad inflamatoria intestinal (EII) es una inflamaci贸n cr贸nica del tracto digestivo. Incluye condiciones tales como colitis ulcerosa e enfermedad de Crohn. En esta alerta del experto, la Dra. Amanda Johnson, gastroenter贸loga en Mayo Clinic, explica la EII y si la dieta puede ayudar.

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Inflammatory bowel disease (IBD) is a chronic inflammation of the digestive tract. It includes conditions such as ulcerative colitis and Crohn's disease. In this expert alert, Amanda Johnson, M.D., a gastroenterologist at Mayo Clinic, helps explain IBD and whether diet can help.

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Uma descoberta feita por pesquisadores da Mayo Clinic pode ajudar a explicar por que a imunoterapia n茫o tem sido 煤til para muitos pacientes com c芒ncer colorretal metast谩tico. Nas descobertas publicadas na Clinical Cancer Research, a equipe identificou prote铆nas espec铆ficas 鈥� fibronectina e actina do m煤sculo liso 鈥� dentro dos tecidos do c芒ncer colorretal que est茫o associados 脿 resist锚ncia ao tratamento imunoter谩pico.

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Experts in nutrition science from across the University of Miami offer their thoughts on some of the best foods to help us ward off chronic disease.

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A doen莽a inflamat贸ria intestinal (DII) 茅 uma inflama莽茫o cr么nica do trato digestivo. Ela inclui condi莽玫es como colite ulcerativa e doen莽a de Crohn. Neste alerta do especialista, a Dra. Amanda Johnson, gastroenterologista na Mayo Clinic, explica a DII e se a dieta pode ajudar.