The research team led by Dr. Hyunwoo Kim and Dr. Myungae Bae at the Korea Research Institute of Chemical Technology (KRICT) has developed the nano-probe-based quantitative stiffness measurement technique for a non-alcoholic fatty liver disease (NAFLD) simulate artificial organoid model while minimizing tissue damage.
Liver transplants are becoming a new treatment option for certain colorectal cancer patients whose cancer has spread to their liver and are ineligible for other surgical options. This innovative approach is providing hope to colorectal cancer patients who otherwise are often faced with a grim prognosis.
Yale Department of Surgery oncologists and trainees at Yale Cancer Center will present new findings at the Society of Surgical Oncology (SSO) Annual Meeting in Tampa, Fla., from March 27鈥�29. The conference focuses on improving surgical cancer care for patients through educational sessions as well as oral and poster presentations for surgical oncologists, researchers, and patient advocates.
Following a comprehensive national search, Cedars-Sinai has appointed David E. Cohen, MD, PhD, as the new chair of the Department of Medicine, effective July 1.
Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. The virus evades immune responses and antiviral therapies due to the persistence of covalently closed circular DNA (cccDNA), which serves as a viral reservoir.
In the March issue of The American Journal of Gastroenterology: The effect of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on gastric retention before endoscopy, resumption of blood thinners after colorectal submucosal dissection, and the utility of inpatient GI consults to clear patients for transesophageal echocardiogram.
A recent study unveils how stromal interaction molecule 1 (STIM1), a protein involved in calcium signaling, plays a pivotal role in the resistance of liver cancer to sorafenib, a key treatment for advanced hepatocellular carcinoma (HCC).
A recent study has unveiled a new mechanism driving hepatocellular carcinoma (HCC) progression through the acetylation of pyruvate dehydrogenase complex (PDC) component X (PDHX), a critical component of the PDC. This modification disrupts PDC assembly, inhibits its function, and shifts metabolism towards aerobic glycolysis, promoting tumor growth. The findings highlight PDHX acetylation as both a potential biomarker and therapeutic target, offering new possibilities for liver cancer treatment and advancing our understanding of cancer cell metabolism.
The Cedars-Sinai Comprehensive Transplant Center and the Smidt Heart Institute set a new record in 2024 by completing 682 solid organ transplants鈥攖he most the medical center has performed in a year鈥攁s patient survival outcomes continued to meet or exceed the national average.
An artificial intelligence (AI) program can identify chronic liver disease from videos taken during a common heart test known as an echocardiogram, Cedars-Sinai investigators report.
Cirujanos de Mayo Clinic descubrieron que un enfoque innovador puede ayudar a los pacientes con obesidad a recibir atenci贸n vital. La obesidad puede ser una barrera para el transplante de h铆gado. La Dra. Julie Heimbach, directora del Centro de Trasplantes de Mayo Clinic en Rochester, Minnesota, afirma que la combinaci贸n de la cirug铆a de manga g谩strica, un tipo de cirug铆a bari谩trica, con el trasplante de h铆gado, es eficaz para hacer frente a ambos problemas de salud.
The potential of induced pluripotent stem cells (iPSCs) for modeling and treating metabolic associated fatty liver disease (MAFLD) and metabolic associated steatohepatitis (MASH) is emerging. MAFLD is a growing global health concern, curren
A study finds a troubling rise in 'deaths of despair' in the U.S. from 1999 to 2021, using the International Classification of Diseases. These deaths, defined by 19 underlying causes such as chronic hepatitis, liver cirrhosis, suicide, drug overdoses, and alcohol-related conditions, increased two-and-a-half-fold over two decades. By 2021, deaths of despair would have become the fifth leading cause of death in the U.S., surpassing 176,000 fatalities, and ranking just behind heart disease, cancer, COVID-19 and accidents.
The liver is an underappreciated, but dependable organ with superhero-like powers.
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