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Gastric bypass is the most clinically and cost effective form of interventional surgery for people living with severe obesity, reveals landmark research. The new University of Bristol-led trial, funded by the National Institute for Health and Care Research (NIHR), is published today [31 March] in the Lancet Diabetes & Endocrinology journal.

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Most patients with Alzheimer's disease and Alzheimer's Disease Related Dementias (ADRD) experience the gradual onset and progression of cognitive symptoms, leading to decline over years or decades. However, in a small subset of patients, symptoms begin rapidly, leading to dementia within one year and complete incapacitation within two years of symptom onset.

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The Association of American Cancer Institutes (AACI) remains strongly opposed to the indiscriminate firing of dedicated public servants across the federal government.

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A new 3D printed customizable hydrogel performed well in preclinical trials with several different types of meniscal tears

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A major reorganization of the U.S. Department of Health and Human Services (HHS)鈥攊ncluding massive cuts to the federal workforce鈥攖hreatens scientific progress that drives our economy and improves the public鈥檚 health.

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He will deliver prerecorded remarks at the 2025 ASBMB Annual Meeting in Chicago.

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Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study led by Michigan Medicine. The findings suggest that attending higher education may enable people to retain greater cognitive ability until a critical threshold of brain injury is reached after a stroke.

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Wistar Institute scientists and collaborators describe a next-generation vaccination technology that combines plasmid DNA with a lipid nanoparticle delivery system.

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Researchers at the National Institutes of Health (NIH) have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis pigmentosa.

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New research from UChicago upends traditional views on how synaptic plasticity supports memory and learning.

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Three decades of landmark research into type 2 diabetes prevention abruptly ended this month due to government funding cuts.

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A new large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without compromising the safety of patients.

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Adding an anti-obesity medication just one month after behavioral therapy begins鈥攔ather than waiting the currently recommended six months鈥攃an more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania.

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A protein called angiopoietin-2 (ANGPT2) can both inhibit and encourage blood vessel changes critical for sepsis, a leading cause of hospital deaths worldwide, a new study led by UT Southwestern Medical Center researchers shows.

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The immune system typically can ramp up the body鈥檚 defenses to clear out an invading threat without issue. Glitches can happen, however, with sepsis occurring when the mustered army of cells also attacks the body鈥檚 own tissues and organs as if they were enemy combatants.

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The study co-led by Dr. Elizabeth Claus of Yale Cancer Center showed an increased presence of haloalkane-associated mutational signatures in the firefighters鈥� tumors.

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Gut microbes shape pancreas development in infancy, leading to long-term changes in diabetes risk, new research in mice has found. The results could ultimately help doctors reduce the risk of type 1 diabetes鈥攐r potentially even restore lost pancreatic function in adulthood鈥攚ith microbes that help the pancreas heal.

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Scientists at St. Jude Children鈥檚 Research Hospital used positron emission tomography (PET) with edaravone, a drug used to treat ALS, to detect oxidative stress, which leads to brain damage, offering a clear path to detecting neurological conditions.