A new multi-center study co-led by scientists from UCLA Health has uncovered critical genetic insights into a group of rare disorders affecting intestinal epithelial cell function, paving the way for targeted therapies that could significantly improve patient outcomes.
Adding an anti-obesity medication just one month after behavioral therapy begins鈥攔ather than waiting the currently recommended six months鈥攃an more than double weight loss for patients who struggle initially with lifestyle changes alone, according to new research published in Nature Medicine from a team at the Perelman School of Medicine at the University of Pennsylvania.
More than 90% of the adult population in the U.S. is or has been infected with Epstein Barr virus (EBV). EBV is a highly contagious member of the herpes virus family, best known for causing infectious mononucleosis ("mono") and for its association with several cancers and autoimmune diseases. Kidney transplant patients who鈥檝e never been exposed to EBV but receive organs from a donor who carried the virus may develop a life-threatening post-transplant complication called lymphoproliferative disorder (PTLD), according to a new study from the Perelman School of Medicine at the University of Pennsylvania. An estimated 4 to 5 percent of adult kidney transplants 鈥� as many as 1200 patients per year 鈥� could be at risk of the condition, in which the body鈥檚 immune system gets confused and immune cells can grow out of control and act like cancer. The findings were recently published in Annals of Internal Medicine.
The study identified specific neurotransmitters and brain cells that are involved in alcohol-induced insomnia. This work could ultimately lead to targeted treatments for alcohol-related sleep loss, helping people recover from alcohol use disorder.
Improved patterns of anti-diabetic medication use and declining rates of various life-threatening acute diabetes complications are closing the disparities gap for American Indian and Alaska Native populations with Type 2 diabetes.
UW Medicine researchers found that patients who underwent the stone-moving ultrasound procedure had a 70% lower risk of such a recurrence. The Journal of Urology published the findings in August.
Until recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes 鈥� such as viruses and fungi 鈥� inhabit the human bladder and urinary tract, known collectively as the 鈥渦robiome.鈥� Now in study that is one of the first of its kind, Dr.
New research led by Ayyalusamy Ramamoorthy, a professor at the FAMU-FSU College of Engineering and the Florida State University-headquartered National High Magnetic Field Laboratory, shows how zinc, pH levels and insulin work together to inhibit the buildup of protein clumps that contribute to Type 2 diabetes.
A two-year study found that spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus鈥� omicron subvariant.
A new study finds that the longer a person has type 2 diabetes, the more likely they may be to experience changes in brain structure. MRI results, researchers say, indicate the negative effects longstanding diabetes may have on brain health outcomes and emphasize the importance of preventing early onset type 2 diabetes.
Researchers at Vanderbilt University Medical Center have received a four-year, $28 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, to study the relationship between COVID-19 and diabetes.
New insights into the underlying mechanisms of Type 2 diabetes and novel potential therapeutic targets for the disease were revealed in a recent study.
Conventional wisdom holds that storing fat around your belly puts you at increased risk for type 2 diabetes. But surprising new findings from the University of Virginia School of Medicine suggest that naturally occurring variations in our genes can lead some people to store fat at the waist but also protect them from diabetes.
People who carry the gene variant associated with the strongest risk for Alzheimer鈥檚 disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems, according to a study published in the July 26, 2023, online issue of Neurology庐, the medical journal of the American Academy of Neurology. The gene variant associated with this increased risk of Alzheimer鈥檚 is called APOE e4.
Understanding how this blood-sugar detection system works and how these neurocircuits operate would give researchers and doctors greater insights into how our brains regulate our blood sugar and, perhaps, how to target them therapeutically to treat metabolic diseases like diabetes and obesity, according to the study authors.
In a study led by Johns Hopkins Medicine, in collaboration with Yale School of Medicine, researchers have identified a biomarker found via a simple urine test that can be used to diagnose acute tubulointerstitial nephritis (AIN), a medical condition that causes inflammation of the kidneys and can lead to acute kidney injury (AKI) 鈥� a sudden loss of kidney function. Experts say a kidney biopsy is often required to diagnose AIN because there are no disease-specific signs or symptoms.
Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.
Researchers with UC San Diego School of Medicine identified a potential new drug that improved liver fibrosis in patients with NASH by 27%.
Results from a new study of diabetic foot ulcers and the risk of wound recurrence show that a new approach can help health care workers measure the likelihood that the wound will reopen in the future.
Monthly cash payments to eligible families under the temporary pandemic-era expansion of the federal Child Tax Credit led to better adult health and food security, new UCLA-led research suggests.
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